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Schizophrenic brains are thus (on average) different in terms of total tissue volume, and activity.

However, there is most often no obvious single point of structural damage (a "lesion") to point at as the specific location in the brain where schizophrenia is happening.

Considered as a whole, these numerous and methodologically distinct results suggest converging and compelling evidence for the idea that schizophrenia is basically a biologically based brain disease.


“There’s something about being able to put my helmet over my face right before I race that takes away the outside chaos and keeps me focused.

While the dopamine hypothesis has been dominant for a long time, it has taken a research beating in recent years, and it is no longer so clear that dopamine alone is responsible for causing schizophrenia.


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